Focalin_XR
Category
Focalin_XR Brand names, Focalin_XR Analogs
Focalin_XR Brand Names Mixture
No information avaliable
Focalin_XR Chemical_Formula
C14H19NO2
Focalin_XR RX_link
http://www.rxlist.com/cgi/generic/methphen.htm
Focalin_XR fda sheet
Focalin_XR msds (material safety sheet)
Focalin_XR Synthesis Reference
M. Hartmann, L. Panizzon, U.S. Pat. 2,507,631 (1950)
Focalin_XR Molecular Weight
233.306 g/mol
Focalin_XR Melting Point
224-226oC
Focalin_XR H2O Solubility
1255mg/L
Focalin_XR State
Solid
Focalin_XR LogP
3.192
Focalin_XR Dosage Forms
Tablets; Tablets (sustained release)
Focalin_XR Indication
For use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Focalin_XR Pharmacology
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine.
Focalin_XR Absorption
Readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. Bioavailability is low (approximately 30%)
Focalin_XR Toxicity
Symptoms of overdose include vomiting, agitation, tremors, hyperreflexia, muscle twitching, convulsions (may be followed by coma), euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, mydriasis, and dryness of mucous membranes. LD50=190mg/kg (orally in mice)
Focalin_XR Patient Information
Focalin_XR Organisms Affected
Humans and other mammals
