Focalin
Category
Focalin Brand names, Focalin Analogs
Focalin Brand Names Mixture
No information avaliable
Focalin Chemical_Formula
C14H19NO2
Focalin RX_link
http://www.rxlist.com/cgi/generic/methphen.htm
Focalin fda sheet
Focalin msds (material safety sheet)
Focalin Synthesis Reference
M. Hartmann, L. Panizzon, U.S. Pat. 2,507,631 (1950)
Focalin Molecular Weight
233.306 g/mol
Focalin Melting Point
224-226oC
Focalin H2O Solubility
1255mg/L
Focalin State
Solid
Focalin LogP
3.192
Focalin Dosage Forms
Tablets; Tablets (sustained release)
Focalin Indication
For use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Focalin Pharmacology
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine.
Focalin Absorption
Readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. Bioavailability is low (approximately 30%)
Focalin Toxicity
Symptoms of overdose include vomiting, agitation, tremors, hyperreflexia, muscle twitching, convulsions (may be followed by coma), euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, mydriasis, and dryness of mucous membranes. LD50=190mg/kg (orally in mice)
Focalin Patient Information
Focalin Organisms Affected
Humans and other mammals
