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Fluniget Brand names, Fluniget Analogs

Fluniget Brand Names Mixture

  • No information avaliable

Fluniget Chemical_Formula

C13H8F2O3

Fluniget RX_link

http://www.rxlist.com/cgi/generic3/diflunisal.htm

Fluniget fda sheet

Fluniget msds (material safety sheet)

Fluniget MSDS

Fluniget Synthesis Reference

No information avaliable

Fluniget Molecular Weight

250.198 g/mol

Fluniget Melting Point

210-221 oC

Fluniget H2O Solubility

Practically insoluble (14.5 mg/L) at neutral or acidic pH.

Fluniget State

Solid

Fluniget LogP

3.876

Fluniget Dosage Forms

Tablets for oral administration (250 mg or 500 mg)

Fluniget Indication

For acute or long-term use for symptomatic treatment of mild to moderate pain, osteoarthritis, and rheumatoid arthritis.

Fluniget Pharmacology

Diflunisal is a nonsteroidal drug with analgesic, anti-inflammatory and antipyretic properties. It is a peripherally-acting non-narcotic analgesic drug. Habituation, tolerance and addiction have not been reported. Diflunisal is a difluorophenyl derivative of salicylic acid. Chemically, diflunisal differs from aspirin (acetylsalicylic acid) in two respects. The first of these two is the presence of a difluorophenyl substituent at carbon 1. The second difference is the removal of the 0-acetyl group from the carbon 4 position. Diflunisal is not metabolized to salicylic acid, and the fluorine atoms are not displaced from the difluorophenyl ring structure.

Fluniget Absorption

Rapidly and completely absorbed following oral administration, with a bioavailability of 80-90%.

Fluniget side effects and Toxicity

Oral LD50 in rat, mouse, and rabbit is 392 mg/kg, 439 mg/kg, and 603 mg/kg, respectively. Symptoms of overdose include coma, tachycardia, stupor, and vomiting. The lowest dose without the presence of other medicines which caused death was 15 grams.

Fluniget Patient Information

Fluniget Organisms Affected

Humans and other mammals