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Fludrone Brand names, Fludrone Analogs

Fludrone Brand Names Mixture

  • No information avaliable

Fludrone Chemical_Formula

C21H29FO5

Fludrone RX_link

http://www.rxlist.com/cgi/generic/fludro.htm

Fludrone fda sheet

Fludrone msds (material safety sheet)

Fludrone MSDS

Fludrone Synthesis Reference

No information avaliable

Fludrone Molecular Weight

380.45 g/mol

Fludrone Melting Point

No information avaliable

Fludrone H2O Solubility

140 mg/L

Fludrone State

Solid

Fludrone LogP

1.49

Fludrone Dosage Forms

Tablet

Fludrone Indication

For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.

Fludrone Pharmacology

Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.

Fludrone Absorption

No information avaliable

Fludrone side effects and Toxicity

Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.

Fludrone Patient Information

Fludrone Organisms Affected

Humans and other mammals