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Fibratol Brand names, Fibratol Analogs

Fibratol Brand Names Mixture

  • No information avaliable

Fibratol Chemical_Formula

C15H22O3

Fibratol RX_link

http://www.rxlist.com/cgi/generic/gemfib.htm

Fibratol fda sheet

Fibratol FDA

Fibratol msds (material safety sheet)

Fibratol Synthesis Reference

P. L. CREGER, U.S. Pat. 3,674,836 (1972)

Fibratol Molecular Weight

250.333 g/mol

Fibratol Melting Point

61-63 oC

Fibratol H2O Solubility

10 mg/mL (in base)

Fibratol State

Solid

Fibratol LogP

4.242

Fibratol Dosage Forms

Tablets; Capsules

Fibratol Indication

For treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.

Fibratol Pharmacology

Gemfibrozil, a fibric acid antilipemic agent similar to clofibrate, is used to treat hyperlipoproteinemia and as a second-line therapy for type IIb hypercholesterolemia. It acts to reduce triglyceride levels, reduce VLDL levels, reduce LDL levels (moderately), and increase HDL levels (moderately).

Fibratol Absorption

Well absorbed from gastrointestinal tract (within 1-2 hours).

Fibratol side effects and Toxicity

Oral, mouse: LD50 = 3162 mg/kg. Symptoms of overdose include abdominal cramps, diarrhea, joint and muscle pain, nausea, and vomiting.

Fibratol Patient Information

Gemfibrozil is used to lower high triglyceride and cholesterol levels. Notify your physician if you are pregnant or nursing. Gemfibrozil should be taken 30 minutes before the morning and evening meals. This medication may cause dizziness or blurred vision; use caution while driving or operating hazardous machinery. Gemfibrozil may cause an increase in blood sugar. If you have diabetes mellitus, carefully monitor blood sugar levels. Notify your physician if you develop severe stomach pain, muscle pain or weakness, or unexplained fever.

Fibratol Organisms Affected

Humans and other mammals