Fenhydren
Fenhydren Brand names, Fenhydren Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Fenhydren Brand Names Mixture
- No information avaliable
Fenhydren Chemical_Formula
C15H10O2
Fenhydren RX_link
No information avaliable
Fenhydren fda sheet
Fenhydren msds (material safety sheet)
Fenhydren Synthesis Reference
No information avaliable
Fenhydren Molecular Weight
222.239 g/mol
Fenhydren Melting Point
148-151 oC
Fenhydren H2O Solubility
27 mg/L (at 20 oC)
Fenhydren State
Solid
Fenhydren LogP
2.917
Fenhydren Dosage Forms
Tablet
Fenhydren Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Fenhydren Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Fenhydren Absorption
Absorbed slowly from the gastrointestinal tract.
Fenhydren side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Fenhydren Patient Information
No information avaliable
Fenhydren Organisms Affected
Humans and other mammals
