Femstat
Femstat Brand names, Femstat Analogs
Femstat Brand Names Mixture
- No information avaliable
Femstat Chemical_Formula
C19H17Cl3N2S
Femstat RX_link
http://www.rxlist.com/cgi/generic2/butoconazole.htm
Femstat fda sheet
Femstat msds (material safety sheet)
Femstat Synthesis Reference
No information avaliable
Femstat Molecular Weight
411.776 g/mol
Femstat Melting Point
Melts at about 159°C with decomposition (nitrate salt)
Femstat H2O Solubility
Nitrate salt: 0.26 mg/ml (practically insoluble)
Femstat State
Solid
Femstat LogP
6.512
Femstat Dosage Forms
Vaginal cream (2%)
Femstat Indication
For the local treatment of vulvovaginal candidiasis (infections caused by Candida)
Femstat Pharmacology
Butoconazole is an imidazole derivative that has fungicidal activity in vitro against Candida spp. and has been demonstrated to be clinically effective against vaginal infections due to Candida albicans. Candida albicans has been identified as the predominant species responsible for vulvovaginal candidasis.
Femstat Absorption
Following vaginal administration of butoconazole nitrate vaginal cream, 2% to 3 women, 1.7% (range 1.3-2.2%) of the dose was absorbed on average.
Femstat side effects and Toxicity
Oral, rat: LD50 = >1720 mg/kg.
Femstat Patient Information
Femstat Organisms Affected
Fungi, yeast and protozoans
