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Felogard Brand names, Felogard Analogs

Felogard Brand Names Mixture

  • No information avaliable

Felogard Chemical_Formula

C18H19Cl2NO4

Felogard RX_link

http://www.rxlist.com/cgi/generic2/felo.htm

Felogard fda sheet

Felogard FDA

Felogard msds (material safety sheet)

Felogard Synthesis Reference

P. B. Berntsson et al., U.S. Pat. 4,264,611 (1980)

Felogard Molecular Weight

384.253 g/mol

Felogard Melting Point

145oC

Felogard H2O Solubility

19.7 mg/L

Felogard State

Solid

Felogard LogP

4.121

Felogard Dosage Forms

Oral tablets

Felogard Indication

For the treatment of hypertension

Felogard Pharmacology

Felodipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Felodipine is similar to other peripheral vasodilators. Felodipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes blocking the calcium channels. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Felogard Absorption

15%

Felogard side effects and Toxicity

excessive peripheral vasodilation with marked hypotension and possibly bradycardia

Felogard Patient Information

Information for the Patient

Patients should be instructed to take felodipine whole and not to crush or chew the
tablets. They should be told that mild gingival hyperplasia (gum swelling) has been
reported. Good dental hygiene decreases its incidence and severity.

Note: As with many other drugs, certain advice to patients being treated with felodipine
is warranted. This information is intended to aid in the safe and effective use of this
medication. It is not a disclosure of all possible adverse or intended effects.

Felogard Organisms Affected

Humans and other mammals