Felbamate

• Antiepileptic Agents
• Anticonvulsants
• Neuroprotective Agents
• ATC:N03AX10

• Felbamyl
• Felbatol
• Taloxa

• No information avaliable

C₁₁H₁₄N₂O₄

http://www.rxlist.com/cgi/generic3/felbamate.htm

Felbamate MSDS

No information avaliable

238.24 g/mol

151.5 ^oC

Slightly soluble in water

Solid

0.76

Tablet; Suspension

For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and/or liver failure is deemed acceptable in light of the benefits conferred by its use.

Felbamate is an antiepileptic indicated as monotherapy or as an adjunct to other anticonvulsants for the treatment of partial seizures resulting from epilepsy. Receptor-binding studies in vitro indicate that felbamate has weak inhibitory effects on GABA-receptor binding, benzodiazepine receptor binding, and is devoid of activity at the MK-801 receptor binding site of the NMDA receptor-ionophore complex. However, felbamate does interact as an antagonist at the strychnine-insensitive glycine recognition site of the NMDA receptor-ionophore complex.

>90%

LD₅₀=5000 mg/kg (Orally in rats)

Patient Information:

Felmabate can cause severe blood abnormality, hepatic failure and other fatal
conditions. Talk about the risks and side effects with your doctor before taking it.

Do not stop the medication without consulting your doctor. Finish the medication
even if you feel better.

Humans and other mammals