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F3T Brand names, F3T Analogs

F3T Brand Names Mixture

  • No information avaliable

F3T Chemical_Formula

C41H42N4O8

F3T RX_link

http://www.rxlist.com/cgi/generic2/verteporfin.htm

F3T fda sheet

F3T FDA

F3T msds (material safety sheet)

F3T Synthesis Reference

No information avaliable

F3T Molecular Weight

718.794 g/mol

F3T Melting Point

No information avaliable

F3T H2O Solubility

No information avaliable

F3T State

Solid

F3T LogP

3.743

F3T Dosage Forms

Powder for solution to be mixed for injection (2mg verteporfin/mL reconstituted verteporfin)

F3T Indication

For the treatment of patients with predominantly classic subfoveal choroidal neovascularization due to age-related macular degeneration, pathologic myopia or presumed ocular histoplasmosis.

F3T Pharmacology

Verteporfin, otherwise known as benzoporphyrin derivative, is a medication used in conjunction with laser treatment to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.

F3T Absorption

No information avaliable

F3T side effects and Toxicity

Overdose of drug and/or light in the treated eye may result in nonperfusion of normal retinal vessels with the possibility of severe decrease in vision that could be permanent. An overdose of drug will also result in the prolongation of the period during which the patient remains photosensitive to bright light.

F3T Patient Information

F3T Organisms Affected

Humans and other mammals