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F3DThd Brand names, F3DThd Analogs

F3DThd Brand Names Mixture

  • No information avaliable

F3DThd Chemical_Formula

C41H42N4O8

F3DThd RX_link

http://www.rxlist.com/cgi/generic2/verteporfin.htm

F3DThd fda sheet

F3DThd FDA

F3DThd msds (material safety sheet)

F3DThd Synthesis Reference

No information avaliable

F3DThd Molecular Weight

718.794 g/mol

F3DThd Melting Point

No information avaliable

F3DThd H2O Solubility

No information avaliable

F3DThd State

Solid

F3DThd LogP

3.743

F3DThd Dosage Forms

Powder for solution to be mixed for injection (2mg verteporfin/mL reconstituted verteporfin)

F3DThd Indication

For the treatment of patients with predominantly classic subfoveal choroidal neovascularization due to age-related macular degeneration, pathologic myopia or presumed ocular histoplasmosis.

F3DThd Pharmacology

Verteporfin, otherwise known as benzoporphyrin derivative, is a medication used in conjunction with laser treatment to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.

F3DThd Absorption

No information avaliable

F3DThd side effects and Toxicity

Overdose of drug and/or light in the treated eye may result in nonperfusion of normal retinal vessels with the possibility of severe decrease in vision that could be permanent. An overdose of drug will also result in the prolongation of the period during which the patient remains photosensitive to bright light.

F3DThd Patient Information

F3DThd Organisms Affected

Humans and other mammals