PharmacyCodes



F-Cortef en es it fr

F-Cortef Brand names, F-Cortef Analogs

F-Cortef Brand Names Mixture

  • No information avaliable

F-Cortef Chemical_Formula

C21H29FO5

F-Cortef RX_link

http://www.rxlist.com/cgi/generic/fludro.htm

F-Cortef fda sheet

F-Cortef msds (material safety sheet)

F-Cortef MSDS

F-Cortef Synthesis Reference

No information avaliable

F-Cortef Molecular Weight

380.45 g/mol

F-Cortef Melting Point

No information avaliable

F-Cortef H2O Solubility

140 mg/L

F-Cortef State

Solid

F-Cortef LogP

1.49

F-Cortef Dosage Forms

Tablet

F-Cortef Indication

For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.

F-Cortef Pharmacology

Fludrocortisone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is indicated as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison’s disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.

F-Cortef Absorption

No information avaliable

F-Cortef side effects and Toxicity

Effects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.

F-Cortef Patient Information

F-Cortef Organisms Affected

Humans and other mammals