Exna
Exna Brand names, Exna Analogs
Exna Brand Names Mixture
- No information avaliable
Exna Chemical_Formula
C15H14ClN3O4S3
Exna RX_link
No information avaliable
Exna fda sheet
Exna msds (material safety sheet)
Exna Synthesis Reference
No information avaliable
Exna Molecular Weight
431.94 g/mol
Exna Melting Point
231.5 oC
Exna H2O Solubility
8.91 mg/L
Exna State
Solid
Exna LogP
2.918
Exna Dosage Forms
Tablet
Exna Indication
For the treatment of high blood pressure and management of edema.
Exna Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Exna Absorption
Absorbed in the digestive tract.
Exna side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Exna Patient Information
Exna Organisms Affected
Humans and other mammals
