Etacrynic acid en es it fr

Etacrynic acid Brand names, Etacrynic acid Analogs

Etacrynic acid Brand Names Mixture

  • No information avaliable

Etacrynic acid Chemical_Formula

C13H12Cl2O4

Etacrynic acid RX_link

http://www.rxlist.com/cgi/generic3/edecrin.htm

Etacrynic acid fda sheet

Etacrynic_acid FDA

Etacrynic acid msds (material safety sheet)

Etacrynic_acid MSDS

Etacrynic acid Synthesis Reference

No information avaliable

Etacrynic acid Molecular Weight

303.137 g/mol

Etacrynic acid Melting Point

122.5 oC

Etacrynic acid H2O Solubility

No information avaliable

Etacrynic acid State

Solid

Etacrynic acid LogP

3.414

Etacrynic acid Dosage Forms

Tablet (25, 50 mg); Powder for solution

Etacrynic acid Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Etacrynic acid Pharmacology

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Etacrynic acid Absorption

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Etacrynic acid side effects and Toxicity

Overdosage may lead to excessive diuresis with electrolyte depletion.

Etacrynic acid Patient Information

No information avaliable

Etacrynic acid Organisms Affected

Humans and other mammals