Esomeprazole Sodium

Esomeprazole Sodium Brand names, Esomeprazole Sodium Analogs

Esomeprazole Sodium Brand Names Mixture

No information avaliable

Esomeprazole Sodium Chemical_Formula

C₁₇H₁₉N₃O₃S

Esomeprazole Sodium RX_link

http://www.rxlist.com/cgi/generic3/esomeprazole.htm

Esomeprazole Sodium fda sheet

Esomeprazole_Sodium FDA

Esomeprazole Sodium msds (material safety sheet)

Esomeprazole Sodium Synthesis Reference

No information avaliable

Esomeprazole Sodium Molecular Weight

345.417 g/mol

Esomeprazole Sodium Melting Point

155 ^oC

Esomeprazole Sodium H₂O Solubility

Very slightly soluble in water

Esomeprazole Sodium State

Solid

Esomeprazole Sodium LogP

1.078

Esomeprazole Sodium Dosage Forms

Tablet (delayed-release); Delayed-release capsules; IV injection solution; IV iufusion solution

Esomeprazole Sodium Indication

For the treatment of acid-reflux disorders (GERD) and peptic ulcer disease

Esomeprazole Sodium Pharmacology

Esomeprazole is a compound that inhibits gastric acid secretion and is indicated in the treatment of gastroesophageal reflux disease (GERD), the healing of erosive esophagitis, and H. pylori eradication to reduce the risk of duodenal ulcer recurrence. Esomeprazole belongs to a new class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or H2 histamine antagonistic properties, but that suppress gastric acid secretion by specific inhibition of the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the gastric mucosa, Esomeprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.

Esomeprazole Sodium Absorption

90%

Esomeprazole Sodium side effects and Toxicity

Blurred vision, confusion, drowsiness, dry mouthflushingheadache, nausea, rapid heartbeat, sweating

Esomeprazole Sodium Patient Information