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Episedal Brand names, Episedal Analogs

Episedal Brand Names Mixture

  • No information avaliable

Episedal Chemical_Formula

C12H12N2O3

Episedal RX_link

No information avaliable

Episedal fda sheet

Episedal msds (material safety sheet)

Episedal MSDS

Episedal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Episedal Molecular Weight

232.235 g/mol

Episedal Melting Point

174 oC

Episedal H2O Solubility

<0.01 g/100 mL

Episedal State

Solid

Episedal LogP

1.777

Episedal Dosage Forms

Tablet; Elixir

Episedal Indication

For the treatment of Epilepsy

Episedal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Episedal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Episedal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Episedal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Episedal Organisms Affected

Humans and other mammals