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Entecavir
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Entecavir Brand names, Entecavir Analogs

Entecavir Brand Names Mixture

  • No information avaliable

Entecavir Chemical_Formula

C12H15N5O3

Entecavir RX_link

http://www.rxlist.com/cgi/generic4/baraclude.htm

Entecavir fda sheet

Entecavir FDA

Entecavir msds (material safety sheet)

Entecavir Synthesis Reference

No information avaliable

Entecavir Molecular Weight

277.279 g/mol

Entecavir Melting Point

No information avaliable

Entecavir H2O Solubility

Slightly soluble (2.4 mg/mL at pH 7.9, 25oC)

Entecavir State

Solid

Entecavir LogP

No information avaliable

Entecavir Dosage Forms

Film-coated tablets for oral administration (0.5 mg, 1 mg); Oral solution (0.05 mg/mL)

Entecavir Indication

For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Entecavir Pharmacology

Entecavir is a guanosine nucleoside analogue with selective activity against hepatitis B virus (HBV). It is designed to selectively inhibit the Hepatitis B virus, blocking all three steps in the replication process. Entecavir is more efficient than an older Hepatitis B drug, lamivudine.

Entecavir Absorption

Absorption Following oral administration in healthy subjects, entecavir peak plasma concentrations occurred between 0.5 and 1.5 hours. In healthy subjects, the bioavailability of the tablet is 100% relative to the oral solution.

Entecavir side effects and Toxicity

No information avaliable

Entecavir Patient Information

Entecavir Organisms Affected

Hepatitis B