Enoxacin

Enoxacin Brand names, Enoxacin Analogs

Enoxacin Brand Names Mixture

No information avaliable

Enoxacin Chemical_Formula

C₁₅H₁₇FN₄O₃

Enoxacin RX_link

http://www.rxlist.com/cgi/generic2/enoxacin.htm

Enoxacin fda sheet

Enoxacin msds (material safety sheet)

Enoxacin MSDS

Enoxacin Synthesis Reference

No information avaliable

Enoxacin Molecular Weight

320.319 g/mol

Enoxacin Melting Point

220-224 ^oC

Enoxacin H₂O Solubility

3.43 g/L

Enoxacin State

Solid

Enoxacin LogP

0.387

Enoxacin Dosage Forms

200 mg and 400 mg film-coated tablets

Enoxacin Indication

For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria gonorrhoeae, (2) uncomplicated urinary tract infections (cystitis) due to Escherichia coli, Staphylococcus epidermidis, or Staphylococcus saprophyticus, and (3) complicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus epidermidis, or Enterobacter cloacae.

Enoxacin Pharmacology

Enoxacin is a quinolone/fluoroquinolone antibiotic. Enoxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Enoxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Enoxacin may be active against pathogens resistant to drugs that act by different mechanisms.

Enoxacin Absorption

Rapidly absorbed following oral administration, with an absolute oral bioavailability of approximately 90%.

Enoxacin side effects and Toxicity