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Effluderm Brand names, Effluderm Analogs

Effluderm Brand Names Mixture

  • No information avaliable

Effluderm Chemical_Formula


Effluderm RX_link


Effluderm fda sheet

Effluderm FDA

Effluderm msds (material safety sheet)

Effluderm MSDS

Effluderm Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Effluderm Molecular Weight

130.077 g/mol

Effluderm Melting Point


Effluderm H2O Solubility

< 0.1 g/100 mL at 19 °C

Effluderm State


Effluderm LogP


Effluderm Dosage Forms

Topical preparations; Solution for injection

Effluderm Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Effluderm Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Effluderm Absorption


Effluderm side effects and Toxicity

LD50=230mg/kg (orally in mice)

Effluderm Patient Information

Effluderm Organisms Affected

Humans and other mammals