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Efalizumab Brand names, Efalizumab Analogs

Efalizumab Brand Names Mixture

  • No information avaliable

Efalizumab Chemical_Formula

No information avaliable

Efalizumab RX_link


Efalizumab fda sheet

Efalizumab msds (material safety sheet)

Efalizumab Synthesis Reference

sequence listed in Werther WA, Gonzalez TN, O'Connor SJ, McCabe S, Chan B, Hotaling T, Champe M, Fox JA, Jardieu PM, Berman PW, Presta LG. Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1. J Immunol. 1996 Dec 1;157(11):4986-95

Efalizumab Molecular Weight

No information avaliable

Efalizumab Melting Point

61 oC (FAB fragment), 71 oC (whole mAb)-Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).

Efalizumab H2O Solubility

No information avaliable

Efalizumab State


Efalizumab LogP

No information avaliable

Efalizumab Dosage Forms

Solution (Subcutaneous Injection)

Efalizumab Indication

For treatment of psoriasis

Efalizumab Pharmacology

Lymphocyte activation and trafficking to skin play a role in the pathophysiology of chronic plaque psoriasis. In psoriatic skin, ICAM-1 cell surface expression is upregulated on endothelium and keratinocytes. Raptiva inhibits the binding of LFA-1 to the intercellular adhesion molecule-1 (ICAM-1), thereby inhibiting the adhesion of leukocytes to other cell types.

Efalizumab Absorption

No information avaliable

Efalizumab side effects and Toxicity

No information avaliable

Efalizumab Patient Information


Efalizumab Organisms Affected

Humans and other mammals