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Edrophonium Brand names, Edrophonium Analogs

Edrophonium Brand Names Mixture

  • No information avaliable

Edrophonium Chemical_Formula


Edrophonium RX_link


Edrophonium fda sheet

Edrophonium msds (material safety sheet)

Edrophonium MSDS

Edrophonium Synthesis Reference

No information avaliable

Edrophonium Molecular Weight

166.24 g/mol

Edrophonium Melting Point

No information avaliable

Edrophonium H2O Solubility

Appreciable as liquid hydrochloride salt

Edrophonium State


Edrophonium LogP


Edrophonium Dosage Forms

Liquid for injection

Edrophonium Indication

For the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises.

Edrophonium Pharmacology

Edrophonium is a short and rapid-acting anticholinesterase drug. Its effect is manifest within 30 to 60 seconds after injection and lasts an average of 10 minutes. Edrophonium's pharmacologic action is due primarily to the inhibition or inactivation of acetylcholinesterase at sites of cholinergic transmission. Muscarinic receptors are found throughout the body, especially on muscle. Stimulation of these receptors causes to muscle contraction. In myasthenia gravis the body's immune system destroys many of the muscarinic receptors, so that the muscle becomes less responsive to nervous stimulation. Edrophonium chloride increases the amount of acetylcholine at the nerve endings. Increased levels of acetyl choline allow the remaining receptors to function more efficiently.

Edrophonium Absorption

Rapidly absorbed.

Edrophonium side effects and Toxicity

With drugs of this type, muscarine-like symptoms (nausea, vomiting, diarrhea, sweating, increased bronchial and salivary secretions and bradycardia) often appear with overdosage (cholinergic crisis).

Edrophonium Patient Information

No information avaliable

Edrophonium Organisms Affected

Humans and other mammals