Dyclothane
Dyclothane Brand names, Dyclothane Analogs
Dyclothane Brand Names Mixture
- No information avaliable
Dyclothane Chemical_Formula
C22H26N2O2S
Dyclothane RX_link
http://www.rxlist.com/cgi/generic3/relpax.htm
Dyclothane fda sheet
Dyclothane msds (material safety sheet)
Dyclothane Synthesis Reference
No information avaliable
Dyclothane Molecular Weight
382.52 g/mol
Dyclothane Melting Point
No information avaliable
Dyclothane H2O Solubility
Readily soluble as hydrobromide formulation
Dyclothane State
Solid
Dyclothane LogP
3.587
Dyclothane Dosage Forms
Tablet for oral administration (24.2 or 48.5 mg)
Dyclothane Indication
For the acute treatment of migraine with or without aura in adults.
Dyclothane Pharmacology
Eletriptan is a selective 5-hydroxytryptamine 1B/1D receptor agonist. In the anesthetized dog, eletriptan has been shown to reduce carotid arterial blood flow, with only a small increase in arterial blood pressure at high doses. While the effect on blood flow was selective for the carotid arterial bed, decreases in coronary artery diameter were observed. Eletriptan has also been shown to inhibit trigeminal nerve activity in the rat.
Dyclothane Absorption
Well absorbed after oral administration with a mean absolute bioavailability of approximately 50%.
Dyclothane side effects and Toxicity
Based on the pharmacology of the 5-HT1B/1D agonists, hypertension or other more serious cardiovascular symptoms could occur on overdose.
Dyclothane Patient Information
No information avaliable
Dyclothane Organisms Affected
Humans and other mammals
