Dopram en es it fr

Dopram Brand names, Dopram Analogs

Dopram Brand Names Mixture

  • No information avaliable

Dopram Chemical_Formula


Dopram RX_link

Dopram fda sheet

Dopram FDA

Dopram msds (material safety sheet)

Dopram MSDS

Dopram Synthesis Reference

No information avaliable

Dopram Molecular Weight

378.507 g/mol

Dopram Melting Point

No information avaliable

Dopram H2O Solubility

Sparingly soluble

Dopram State


Dopram LogP


Dopram Dosage Forms

Liquid; Solution

Dopram Indication

For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.

Dopram Pharmacology

Doxapram is an analeptic agent (a stimulant of the central nervous system). The respiratory stimulant action is manifested by an increase in tidal volume associated with a slight increase in respiratory rate. A pressor response may result following doxapram administration. Provided there is no impairment of cardiac function, the pressor effect is more marked in hypovolemic than in normovolemic states. The pressor response is due to the improved cardiac output rather than peripheral vasoconstriction. Following doxapram administration, an increased release of catecholamines has been noted.

Dopram Absorption

No information avaliable

Dopram side effects and Toxicity

Intravenous LD50 values in the mouse and rat were approximately 75 mg/kg and in the cat and dog were 40 to 80 mg/kg. Symptoms of overdosage are extensions of the pharmacologic effects of the drug. Excessive pressor effect, tachycardia, skeletal muscle hyperactivity, and enhanced deep tendon reflexes may be early signs of overdosage.

Dopram Patient Information

No information avaliable

Dopram Organisms Affected

Humans and other mammals