Diulo
Category
Diulo Brand names, Diulo Analogs
Diulo Brand Names Mixture
Diulo Chemical_Formula
C18H14Cl4N2O
Diulo RX_link
http://www.rxlist.com/cgi/generic2/micon.htm
Diulo fda sheet
Diulo msds (material safety sheet)
Diulo Synthesis Reference
No information avaliable
Diulo Molecular Weight
416.127 g/mol
Diulo Melting Point
159 - 163 oC
Diulo H2O Solubility
1g/100mL (20°C)
Diulo State
Solid
Diulo LogP
6.02
Diulo Dosage Forms
Topical cream (2%); Vaginal cream (2%); Vaginal suppositories (100mg, 200mg)
Diulo Indication
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
Diulo Pharmacology
Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Miconazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Diulo Absorption
No information avaliable
Diulo Toxicity
Oral, mouse: LD50 = 3800 mg/kg; Oral, rat: LD50 = 3 gm/kg. Ingestion of the amounts of the components contained in a tube of cream are unlikely to produce overdosage and toxic effects.
Diulo Patient Information
No information avaliable
Diulo Organisms Affected
Fungi, yeast and protozoans
