Ditropan
Ditropan Brand names, Ditropan Analogs
Ditropan Brand Names Mixture
- No information avaliable
Ditropan Chemical_Formula
C22H31NO3
Ditropan RX_link
http://www.rxlist.com/cgi/generic/ditropan.htm
Ditropan fda sheet
Ditropan msds (material safety sheet)
Ditropan Synthesis Reference
Brit. pat. 940540 (1963 to Mead Johnson)
Ditropan Molecular Weight
357.486 g/mol
Ditropan Melting Point
129-130 oC
Ditropan H2O Solubility
No information avaliable
Ditropan State
Solid
Ditropan LogP
4.683
Ditropan Dosage Forms
Patch; Syrup; Tablet; Tablet (extended-release)
Ditropan Indication
For the treatment of overactive bladder.
Ditropan Pharmacology
Oxybutynin is an antispasmodic, anticholinergic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Oxybutynin relaxes bladder smooth muscle. Oxybutynin exhibits only one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. Antimuscarinic activity resides predominantly in the R-isomer.
Ditropan Absorption
Rapidly absorbed from gastrointestinal tract.
Ditropan side effects and Toxicity
LD50=1220 mg/kg (Orally in rats, Goldenthal)
Ditropan Patient Information
PATIENT INFORMATION
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.
Patient should be informed that oxybutynin may produce drowsiness or blurred vision. Alcohal may enhance the drowsiness caused by anticholinergic agents. Fever and heat stroke can occur while anticholinergics are administered in the presence of high environmental temparature. Medication should be taken with the aid of liquids at approximately the same time each day. Patients should not chew, divide, or crush tablets.
Ditropan Organisms Affected
Humans and other mammals
