Dindevan en es it fr

Dindevan Brand names, Dindevan Analogs

Dindevan Brand Names Mixture

  • No information avaliable

Dindevan Chemical_Formula

C15H10O2

Dindevan RX_link

No information avaliable

Dindevan fda sheet

Dindevan msds (material safety sheet)

Dindevan MSDS

Dindevan Synthesis Reference

No information avaliable

Dindevan Molecular Weight

222.239 g/mol

Dindevan Melting Point

148-151 oC

Dindevan H2O Solubility

27 mg/L (at 20 oC)

Dindevan State

Solid

Dindevan LogP

2.917

Dindevan Dosage Forms

Tablet

Dindevan Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Dindevan Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Dindevan Absorption

Absorbed slowly from the gastrointestinal tract.

Dindevan side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Dindevan Patient Information

No information avaliable

Dindevan Organisms Affected

Humans and other mammals