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Dimorphone Brand names, Dimorphone Analogs

Dimorphone Brand Names Mixture

  • No information avaliable

Dimorphone Chemical_Formula

C17H19NO3

Dimorphone RX_link

http://www.rxlist.com/cgi/generic/hydromorphone.htm

Dimorphone fda sheet

Dimorphone FDA

Dimorphone msds (material safety sheet)

Dimorphone MSDS

Dimorphone Synthesis Reference

No information avaliable

Dimorphone Molecular Weight

285.338 g/mol

Dimorphone Melting Point

266-267 oC

Dimorphone H2O Solubility

No information avaliable

Dimorphone State

Solid

Dimorphone LogP

1.28 (Roy, SD; Flynn, GL Pharm. Res. 5:580 (1988))

Dimorphone Dosage Forms

Capsule (controlled-delivery); Solution; Tablet

Dimorphone Indication

For the relief of moderate to severe pain such as that due to surgery, cancer, trauma/injury, burns, myocardial infarction and colic.

Dimorphone Pharmacology

Hydromorphone is a hydrogenated ketone derivative of morphine that acts as a narcotic analgesic. It has a shorter duration of action than morphine. Hydromorphone is approximately 8 times more potent on a milligram basis than morphine. In addition, hydromorphone is better absorbed orally than is morphine. In clinical settings, Hydromorphone exerts its principal pharmacological effect on the central nervous system and gastrointestinal tract. Its primary actions of therapeutic value are analgesia and sedation. Hydromorphone appears to increase the patient's tolerance for pain and to decrease discomfort, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Opioids also produce respiratory depression by direct action on brain stem respiratory centers.

Dimorphone Absorption

Better absorbed orally than morphine

Dimorphone side effects and Toxicity

Hydromorphone is a schedule II narcotic which can lead to physical dependence or addiction. High doses lead to respiratory depression, nausea, and vomiting. Overdoses lead to extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdosage, apnea, circulatory collapse, cardiac arrest and death may occur.

Dimorphone Patient Information

http://www.drugs.com/cons/Hydroflumethiazide.html

Dimorphone Organisms Affected

Humans and other mammals