Dimelin
Dimelin Brand names, Dimelin Analogs
Dimelin Brand Names Mixture
- No information avaliable
Dimelin Chemical_Formula
C15H20N2O4S
Dimelin RX_link
No information avaliable
Dimelin fda sheet
Dimelin msds (material safety sheet)
Dimelin Synthesis Reference
No information avaliable
Dimelin Molecular Weight
324.396 g/mol
Dimelin Melting Point
188-190 oC
Dimelin H2O Solubility
3430 mg/L
Dimelin State
Solid
Dimelin LogP
2.954
Dimelin Dosage Forms
Tablet (250, 500 mg)
Dimelin Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Dimelin Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Dimelin Absorption
Rapidly absorbed from the GI tract.
Dimelin side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Dimelin Patient Information
No information avaliable
Dimelin Organisms Affected
Humans and other mammals
