Dihydronorguaiaretic_acid
Category
Dihydronorguaiaretic_acid Brand names, Dihydronorguaiaretic_acid Analogs
Dihydronorguaiaretic_acid Brand Names Mixture
No information avaliable
Dihydronorguaiaretic_acid Chemical_Formula
C22H30O3
Dihydronorguaiaretic_acid RX_link
http://www.rxlist.com/cgi/generic4/megace_es.htm
Dihydronorguaiaretic_acid fda sheet
Dihydronorguaiaretic_acid msds (material safety sheet)
Dihydronorguaiaretic_acid Synthesis Reference
No information avaliable
Dihydronorguaiaretic_acid Molecular Weight
342.472 g/mol
Dihydronorguaiaretic_acid Melting Point
218.0-220.0oC
Dihydronorguaiaretic_acid H2O Solubility
2 µg/mL (at 37°C for the acetate salt)
Dihydronorguaiaretic_acid State
Solid
Dihydronorguaiaretic_acid LogP
3.123
Dihydronorguaiaretic_acid Dosage Forms
Oral suspension containing 125 mg of megestrol acetate per mL; Tablet
Dihydronorguaiaretic_acid Indication
For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.
Dihydronorguaiaretic_acid Pharmacology
Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.
Dihydronorguaiaretic_acid Absorption
Variable, but well absorbed orally.
Dihydronorguaiaretic_acid Toxicity
No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.
Dihydronorguaiaretic_acid Patient Information
No information avaliable
Dihydronorguaiaretic_acid Organisms Affected
Humans and other mammals
