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Dihydrocodeinone Brand names, Dihydrocodeinone Analogs

Dihydrocodeinone Brand Names Mixture

  • Caldomine DH Adulte (Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate)
  • Caldomine DH Enfant (Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate)
  • Coristine-DH Liq (Hydrocodone Bitartrate + Phenylephrine Hydrochloride)
  • Dalmacol (Alcohol Anhydrous + Doxylamine Succinate + Etafedrin Hydrochloride + Hydrocodone Bitartrate + Sodium Citrate)
  • Dimetane Expectorant-DC Syr (Brompheniramine Maleate + Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride + Phenylpropanolamine Hydrochloride)
  • Dimetane Expectorant-DC Syrup (Brompheniramine Maleate + Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride)
  • Hycomine-S (Ammonium Chloride + Hydrocodone Bitartrate + Phenylephrine Hydrochloride + Pyrilamine Maleate)
  • Mercodol with Decapryn (Doxylamine Succinate + Etafedrin Hydrochloride + Hydrocodone Bitartrate + Sodium Citrate)
  • Novahistex Dh Expectorant (Guaifenesin + Hydrocodone Bitartrate + Phenylephrine Hydrochloride)
  • Novahistex Dh Syrup (Hydrocodone Bitartrate + Phenylephrine Hydrochloride)
  • Ratio-Calmydone (Doxylamine Succinate + Etafedrin Hydrochloride + Hydrocodone Bitartrate + Sodium Citrate)
  • Ratio-Coristex-DH (Hydrocodone Bitartrate + Phenylephrine Hydrochloride)
  • Solucodan Syrup (Hydrocodone Bitartrate + Menthol + Potassium Guaiacol Sulphonate + Sodium Citrate)
  • Solucodan-H (Diphenylpyraline Hydrochloride + Hydrocodone Bitartrate + Menthol + Potassium Guaiacol Sulphonate + Sodium Citrate)
  • Triaminic Expectorant DH Syrup (Guaifenesin + Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate)
  • Tussaminic DH Forte Syrup (Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate)
  • Tussaminic DH Pediatric Syrup (Hydrocodone Bitartrate + Pheniramine Maleate + Phenylpropanolamine Hydrochloride + Pyrilamine Maleate)

Dihydrocodeinone Chemical_Formula

C18H21NO3

Dihydrocodeinone RX_link

http://www.rxlist.com/cgi/generic/hydrocod.htm

Dihydrocodeinone fda sheet

Dihydrocodeinone msds (material safety sheet)

Dihydrocodeinone MSDS

Dihydrocodeinone Synthesis Reference

K. Pfister, M. Tishler; U.S. Pat. 2,715,626 (1955)

Dihydrocodeinone Molecular Weight

299.364 g/mol

Dihydrocodeinone Melting Point

198oC

Dihydrocodeinone H2O Solubility

Insoluble

Dihydrocodeinone State

Solid

Dihydrocodeinone LogP

2.041

Dihydrocodeinone Dosage Forms

Tablets; Syrup; Liquid mixtures with other analgesics

Dihydrocodeinone Indication

For relief of moderate to moderately severe pain.

Dihydrocodeinone Pharmacology

Hydrocodone, a semisynthetic opiate agonist and hydrogenated ketone derivative, is similar to other phenanthrene derivatives, such as codeine. Used as an analgesic, hydrocodone is combined with acetaminophen, ibuprofen, or aspirin to treat pain. Used as an antitussive, hydrocodone is combined with phenylephrine, pseudoephedrine, phenylpropanolamine, guaifenesin, pyrilamine, pheniramine, or chlorpheniramine.

Dihydrocodeinone Absorption

Well absorbed from the gastrointestinal tract.

Dihydrocodeinone side effects and Toxicity

Symptoms of overdose include respiratory depression (a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, dizziness, ringing in the ears, confusion, blurred vision, eye problems, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdose, apnea, circulatory collapse, cardiac arrest and death may occur. LD50=85.7mg/kg (subcutaneous, in mice).

Dihydrocodeinone Patient Information

Dihydrocodeinone Organisms Affected

Humans and other mammals