Dicorantil
Dicorantil Brand names, Dicorantil Analogs
Dicorantil Brand Names Mixture
- No information avaliable
Dicorantil Chemical_Formula
C21H29N3O
Dicorantil RX_link
http://www.rxlist.com/cgi/generic2/disopyr.htm
Dicorantil fda sheet
Dicorantil msds (material safety sheet)
Dicorantil Synthesis Reference
No information avaliable
Dicorantil Molecular Weight
339.475 g/mol
Dicorantil Melting Point
94.5-95 oC
Dicorantil H2O Solubility
44.9 mg/L
Dicorantil State
Solid
Dicorantil LogP
3.972
Dicorantil Dosage Forms
Capsule; Tablet (extended-release)
Dicorantil Indication
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.
Dicorantil Pharmacology
Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.
Dicorantil Absorption
Nearly complete
Dicorantil side effects and Toxicity
LD50=580 mg/kg in rats
Dicorantil Patient Information
No information avaliable
Dicorantil Organisms Affected
Humans and other mammals
