Dibucaine
Dibucaine Brand names, Dibucaine Analogs
Dibucaine Brand Names Mixture
- No information avaliable
Dibucaine Chemical_Formula
C20H29N3O2
Dibucaine RX_link
No information avaliable
Dibucaine fda sheet
Dibucaine msds (material safety sheet)
Dibucaine Synthesis Reference
No information avaliable
Dibucaine Molecular Weight
343.463 g/mol
Dibucaine Melting Point
99-101oC (HCl salt)
Dibucaine H2O Solubility
42 mg/L
Dibucaine State
Solid
Dibucaine LogP
3.588
Dibucaine Dosage Forms
Ointment
Dibucaine Indication
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
Dibucaine Pharmacology
Dibucaine is an amide-type local anesthetic, similar to lidocaine.
Dibucaine Absorption
In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.
Dibucaine side effects and Toxicity
Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
Dibucaine Patient Information
No information avaliable
Dibucaine Organisms Affected
Humans and other mammals
