Dibenzyran
Dibenzyran Brand names, Dibenzyran Analogs
Dibenzyran Brand Names Mixture
- No information avaliable
Dibenzyran Chemical_Formula
C18H22ClNO
Dibenzyran RX_link
http://www.rxlist.com/cgi/generic3/phenoxybenz.htm
Dibenzyran fda sheet
Dibenzyran msds (material safety sheet)
Dibenzyran Synthesis Reference
No information avaliable
Dibenzyran Molecular Weight
303.826 g/mol
Dibenzyran Melting Point
39 oC
Dibenzyran H2O Solubility
No information avaliable
Dibenzyran State
Solid
Dibenzyran LogP
4.601
Dibenzyran Dosage Forms
No information avaliable
Dibenzyran Indication
For the treatment of phaeochromocytoma (malignant), benign prostatic hypertrophy and malignant essential hypertension.
Dibenzyran Pharmacology
Phenoxybenzamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phenoxybenzamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phenoxybenzamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phenoxybenzamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.
Dibenzyran Absorption
No information avaliable
Dibenzyran side effects and Toxicity
No information avaliable
Dibenzyran Patient Information
No information avaliable
Dibenzyran Organisms Affected
Humans and other mammals
