Dibenzoazepine
Dibenzoazepine Brand names, Dibenzoazepine Analogs
Dibenzoazepine Brand Names Mixture
- No information avaliable
Dibenzoazepine Chemical_Formula
C18H18ClN3O
Dibenzoazepine RX_link
http://www.rxlist.com/cgi/generic2/loxapineoc.htm
Dibenzoazepine fda sheet
Dibenzoazepine msds (material safety sheet)
Dibenzoazepine Synthesis Reference
Neth. pat. Appl. 6,406,089 corresp to Schmutz et al., U.S. pat. 3,546,226 (1964, 1970 both to Wander)
Dibenzoazepine Molecular Weight
327.808 g/mol
Dibenzoazepine Melting Point
109-110 oC
Dibenzoazepine H2O Solubility
No information avaliable
Dibenzoazepine State
Solid
Dibenzoazepine LogP
3.162
Dibenzoazepine Dosage Forms
Tablet; Capsule; Oral solution; IV solution; IM solution
Dibenzoazepine Indication
For the management of the manifestations of psychotic disorders
Dibenzoazepine Pharmacology
Loxapine, a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Pharmacologically, Loxapine is a tranquilizer for which the exact mode of action has not been established.
Dibenzoazepine Absorption
Systemic bioavailability of the parent drug was only about one third that after an equivalent intramuscular dose (25 mg base) in male volunteers
Dibenzoazepine side effects and Toxicity
LD50=65 mg/kg (Orally in mice)
Dibenzoazepine Patient Information
Dibenzoazepine Organisms Affected
Humans and other mammals
