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Diatrizoic acid sodium salt Brand names, Diatrizoic acid sodium salt Analogs

Diatrizoic acid sodium salt Brand Names Mixture

  • No information avaliable

Diatrizoic acid sodium salt Chemical_Formula

C9H15N5O3

Diatrizoic acid sodium salt RX_link

No information avaliable

Diatrizoic acid sodium salt fda sheet

Diatrizoic acid sodium salt msds (material safety sheet)

Diatrizoic acid sodium salt Synthesis Reference

No information avaliable

Diatrizoic acid sodium salt Molecular Weight

241.247 g/mol

Diatrizoic acid sodium salt Melting Point

250-255 oC (hydrochloride salt)

Diatrizoic acid sodium salt H2O Solubility

>20 mg/mL (dichloride salt)

Diatrizoic acid sodium salt State

Solid

Diatrizoic acid sodium salt LogP

-1.783

Diatrizoic acid sodium salt Dosage Forms

No information avaliable

Diatrizoic acid sodium salt Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatrizoic acid sodium salt Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatrizoic acid sodium salt Absorption

No information avaliable

Diatrizoic acid sodium salt side effects and Toxicity

No information avaliable

Diatrizoic acid sodium salt Patient Information

No information avaliable

Diatrizoic acid sodium salt Organisms Affected

Humans and other mammals