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Diatrizoate sodium salt Brand names, Diatrizoate sodium salt Analogs

Diatrizoate sodium salt Brand Names Mixture

  • No information avaliable

Diatrizoate sodium salt Chemical_Formula

C9H15N5O3

Diatrizoate sodium salt RX_link

No information avaliable

Diatrizoate sodium salt fda sheet

Diatrizoate sodium salt msds (material safety sheet)

Diatrizoate sodium salt Synthesis Reference

No information avaliable

Diatrizoate sodium salt Molecular Weight

241.247 g/mol

Diatrizoate sodium salt Melting Point

250-255 oC (hydrochloride salt)

Diatrizoate sodium salt H2O Solubility

>20 mg/mL (dichloride salt)

Diatrizoate sodium salt State

Solid

Diatrizoate sodium salt LogP

-1.783

Diatrizoate sodium salt Dosage Forms

No information avaliable

Diatrizoate sodium salt Indication

For the treatment of tetrahydrobiopterin (BH4) deficiency.

Diatrizoate sodium salt Pharmacology

Tetrahydrobiopterin (BH4) is used to convert several amino acids, including phenylalanine, to other essential molecules in the body including neurotransmitters. Tetrahydrobiopterin deficiency can be caused by mutations in GTP cyclohydrolase 1 (GCH1), 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1), 6-pyruvoyltetrahydropterin synthase (PTS), and quinoid dihydropteridine reductase (QDPR) genes. These genes make the enzymes that are critical for producing and recycling tetrahydrobiopterin. If one of the enzymes fails to function correctly because of a gene mutation, little or no tetrahydrobiopterin is produced. As a result, phenylalanine from the diet builds up in the bloodstream and other tissues and can damage nerve cells in the brain. High levels of phenylalanine can result in signs and symptoms ranging from temporary low muscle tone to mental retardation, movement disorders, difficulty swallowing, seizures, behavioral problems, progressive problems with development, and an inability to control body temperature.

Diatrizoate sodium salt Absorption

No information avaliable

Diatrizoate sodium salt side effects and Toxicity

No information avaliable

Diatrizoate sodium salt Patient Information

No information avaliable

Diatrizoate sodium salt Organisms Affected

Humans and other mammals