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Diason Brand names, Diason Analogs

Diason Brand Names Mixture

  • No information avaliable

Diason Chemical_Formula

C14H16N2O6S3

Diason RX_link

No information avaliable

Diason fda sheet

Diason msds (material safety sheet)

Diason MSDS

Diason Synthesis Reference

No information avaliable

Diason Molecular Weight

404.485 g/mol

Diason Melting Point

No information avaliable

Diason H2O Solubility

No information avaliable

Diason State

Solid

Diason LogP

-1.064

Diason Dosage Forms

Tablet

Diason Indication

For the treatment of leprosy and dermatitis herpetiformis

Diason Pharmacology

Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Diason Absorption

Rapidly absorbed.

Diason side effects and Toxicity

Oral, rat LD50: 7000 mg/kg

Diason Patient Information

Diason Organisms Affected

Enteric bacteria and other eubacteria