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Destruxol Orchid Spray Brand names, Destruxol Orchid Spray Analogs

Destruxol Orchid Spray Brand Names Mixture

  • No information avaliable

Destruxol Orchid Spray Chemical_Formula

C10H14N2

Destruxol Orchid Spray RX_link

http://www.rxlist.com/cgi/generic2/nicotini.htm

Destruxol Orchid Spray fda sheet

Destruxol_Orchid_Spray FDA

Destruxol Orchid Spray msds (material safety sheet)

Destruxol_Orchid_Spray MSDS

Destruxol Orchid Spray Synthesis Reference

Pinner, Ber. 26, 294 (1893)

Destruxol Orchid Spray Molecular Weight

162.232 g/mol

Destruxol Orchid Spray Melting Point

-79 oC

Destruxol Orchid Spray H2O Solubility

1 g/mL

Destruxol Orchid Spray State

Liquid

Destruxol Orchid Spray LogP

1.305

Destruxol Orchid Spray Dosage Forms

Gum; Inhaler; Patch

Destruxol Orchid Spray Indication

For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.

Destruxol Orchid Spray Pharmacology

Nicotine, the primary alkaloid in tobacco products binds stereo-selectively to nicotinic-cholinergic receptors on autonomic ganglia, the adrenal medulla, neuromuscular junctions and in the brain. Nicotine exerts two effects, a stimulant effect exerted at the locus ceruleus and a reward effect in the limbic system. Itranvenous administration of nicotine causes release of acetylcholine, norepinephrine, dopamine, serotonine, vasopressin, beta-endorphin and ACTH. Nicotine is a highly addictive substance. Nicotine also induces peripheral vasoconstriction, tachycardia and elevated blood pressure. Nicotine inhalers and patches are used to treat smoking withdrawl syndrome. Nicotine is classified as a stimulant of autonomic ganglia.

Destruxol Orchid Spray Absorption

Absorption of nicotine through the buccal mucosa is relatively slow and the high and rapid rise followed by the decline in nicotine arterial plasma concentrations seen with cigarette smoking are not achieved with the inhaler. About 10% of absorbed nicotine is excreted unchanged in urine.

Destruxol Orchid Spray side effects and Toxicity

Symptoms of overdose include nausea, abdominal pain, vomiting, diarrhea, diaphoresis, flushing, dizziness, disturbed hearing and vision, confusion, weakness, palpitations, altered respiration and hypotension. LD50= 24 mg/kg (orally in mice).

Destruxol Orchid Spray Patient Information

A patient information sheet is included in the package of NICOTROL Inhaler cartridges dispensed to the patient. Patients should be encouraged to read the information sheet carefully and to ask their physician and pharmacist about the proper use of the product .

Patients must be advised to keep both used and unused cartridges out of the reach of children and pets.

Destruxol Orchid Spray Organisms Affected

Humans and other mammals