Desloratidine
Desloratidine Brand names, Desloratidine Analogs
Desloratidine Brand Names Mixture
- Clarinex-D 12 Hour Extended Release Tablets (desloratadine + pseudoephedrine)
Desloratidine Chemical_Formula
C19H19ClN2
Desloratidine RX_link
http://www.rxlist.com/cgi/generic3/clarinex.htm
Desloratidine fda sheet
Desloratidine msds (material safety sheet)
Desloratidine Synthesis Reference
No information avaliable
Desloratidine Molecular Weight
310.82 g/mol
Desloratidine Melting Point
No information avaliable
Desloratidine H2O Solubility
No information avaliable
Desloratidine State
Solid
Desloratidine LogP
3.232
Desloratidine Dosage Forms
Syrup; Tablet
Desloratidine Indication
For the relief of symptoms of seasonal allergic rhinitis, pruritus, reduction in the number of hives in patients with chronic idiopathic urticaria.
Desloratidine Pharmacology
Desloratadine is a long-lasting antihistamine. Desloratadine is a second-generation H1-receptor antagonist which has a selective and peripheral H1-antagonist action. Histamine is a chemical that causes many of the signs that are part of allergic reactions, for example, swelling of tissues. Histamine is released from histamine-storing cells (mast cells) and attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cell to be "activated," releasing other chemicals which produce the effects that we associate with allergy. Desloratadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of cells by histamine. Unlike most other antihistamines, Desloratadine does not enter the brain from the blood and, therefore, does not cause drowsiness.
Desloratidine Absorption
No information avaliable
Desloratidine side effects and Toxicity
No information avaliable
Desloratidine Patient Information
No information avaliable
Desloratidine Organisms Affected
Humans and other mammals
