Deoxyepinephrine

Deoxyepinephrine Brand names, Deoxyepinephrine Analogs

Deoxyepinephrine Brand Names Mixture

No information avaliable

Deoxyepinephrine Chemical_Formula

C₈H₁₁NO₂

Deoxyepinephrine RX_link

http://www.rxlist.com/cgi/generic3/dopamine.htm

Deoxyepinephrine fda sheet

Deoxyepinephrine msds (material safety sheet)

Deoxyepinephrine MSDS

Deoxyepinephrine Synthesis Reference

No information avaliable

Deoxyepinephrine Molecular Weight

153.178 g/mol

Deoxyepinephrine Melting Point

82.5 ^oC

Deoxyepinephrine H₂O Solubility

600 g/L

Deoxyepinephrine State

Solid

Deoxyepinephrine LogP

0.548

Deoxyepinephrine Dosage Forms

Solution

Deoxyepinephrine Indication

For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Deoxyepinephrine Pharmacology

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings.

Deoxyepinephrine Absorption

Dopamine is rapidly absorbed from the small intestine.

Deoxyepinephrine side effects and Toxicity

LD₅₀ oral mice = 1460 mg/kg, LD₅₀ oral rats = 1780 mg/kg. Spasm or closing of eyelids, nausea, vomiting, cardiac arrhythmias, involuntary movements of the body including the face, tongue, arms, hand, head, and upper body; hypotension, haemolytic anaemia, urinary retention, duodenal ulcer, sialorrhea, ataxia, abdominal pain, dry mouth, nightmares, tachypnoea, bruxism, confusion, and insomnia.

Deoxyepinephrine Patient Information