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Danilone Brand names, Danilone Analogs

Danilone Brand Names Mixture

  • No information avaliable

Danilone Chemical_Formula

C15H10O2

Danilone RX_link

No information avaliable

Danilone fda sheet

Danilone msds (material safety sheet)

Danilone MSDS

Danilone Synthesis Reference

No information avaliable

Danilone Molecular Weight

222.239 g/mol

Danilone Melting Point

148-151 oC

Danilone H2O Solubility

27 mg/L (at 20 oC)

Danilone State

Solid

Danilone LogP

2.917

Danilone Dosage Forms

Tablet

Danilone Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Danilone Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Danilone Absorption

Absorbed slowly from the gastrointestinal tract.

Danilone side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Danilone Patient Information

No information avaliable

Danilone Organisms Affected

Humans and other mammals