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Danedion Brand names, Danedion Analogs

Danedion Brand Names Mixture

  • No information avaliable

Danedion Chemical_Formula

C15H10O2

Danedion RX_link

No information avaliable

Danedion fda sheet

Danedion msds (material safety sheet)

Danedion MSDS

Danedion Synthesis Reference

No information avaliable

Danedion Molecular Weight

222.239 g/mol

Danedion Melting Point

148-151 oC

Danedion H2O Solubility

27 mg/L (at 20 oC)

Danedion State

Solid

Danedion LogP

2.917

Danedion Dosage Forms

Tablet

Danedion Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Danedion Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Danedion Absorption

Absorbed slowly from the gastrointestinal tract.

Danedion side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Danedion Patient Information

No information avaliable

Danedion Organisms Affected

Humans and other mammals