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Daktarin Brand names, Daktarin Analogs

Daktarin Brand Names Mixture

  • No information avaliable

Daktarin Chemical_Formula

C27H34N2O7

Daktarin RX_link

http://www.rxlist.com/cgi/generic2/moexip.htm

Daktarin fda sheet

Daktarin msds (material safety sheet)

Daktarin Synthesis Reference

No information avaliable

Daktarin Molecular Weight

498.568 g/mol

Daktarin Melting Point

No information avaliable

Daktarin H2O Solubility

Soluble (about 10% weight-to-volume) in distilled water at room temperature as HCl salt.

Daktarin State

Solid

Daktarin LogP

3.31

Daktarin Dosage Forms

Tablets (scored, coated, containing 7.5 mg or 15 mg of moexipril hydrochloride for oral administration)

Daktarin Indication

For treatment of patients with hypertension.

Daktarin Pharmacology

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

Daktarin Absorption

Moexipril is incompletely absorbed, with bioavailability as moexiprilat of about 13% compared to intravenous (I.V.) moexipril (both measuring the metabolite moexiprilat), and is markedly affected by food, which reduces Cmax and AUC by about 70% and 40% respectively after the ingestion of a low-fat breakfast or by 80% and 50% respectively after the ingestion of a high-fat breakfast.

Daktarin side effects and Toxicity

Human overdoses of moexipril have not been reported. In case reports of overdoses with other ACE inhibitors, hypotension has been the principal adverse effect noted. Single oral doses of 2 g/kg moexipril were associated with significant lethality in mice. Rats, however, tolerated single oral doses of up to 3 g/kg.

Daktarin Patient Information

Daktarin Organisms Affected

Humans and other mammals