DF B
DF B Brand names, DF B Analogs
DF B Brand Names Mixture
- No information avaliable
DF B Chemical_Formula
C20H29N3O2
DF B RX_link
No information avaliable
DF B fda sheet
DF B msds (material safety sheet)
DF B Synthesis Reference
No information avaliable
DF B Molecular Weight
343.463 g/mol
DF B Melting Point
99-101oC (HCl salt)
DF B H2O Solubility
42 mg/L
DF B State
Solid
DF B LogP
3.588
DF B Dosage Forms
Ointment
DF B Indication
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
DF B Pharmacology
Dibucaine is an amide-type local anesthetic, similar to lidocaine.
DF B Absorption
In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.
DF B side effects and Toxicity
Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
DF B Patient Information
No information avaliable
DF B Organisms Affected
Humans and other mammals
