DFOA
DFOA Brand names, DFOA Analogs
DFOA Brand Names Mixture
- No information avaliable
DFOA Chemical_Formula
C20H29N3O2
DFOA RX_link
No information avaliable
DFOA fda sheet
DFOA msds (material safety sheet)
DFOA Synthesis Reference
No information avaliable
DFOA Molecular Weight
343.463 g/mol
DFOA Melting Point
99-101oC (HCl salt)
DFOA H2O Solubility
42 mg/L
DFOA State
Solid
DFOA LogP
3.588
DFOA Dosage Forms
Ointment
DFOA Indication
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
DFOA Pharmacology
Dibucaine is an amide-type local anesthetic, similar to lidocaine.
DFOA Absorption
In general, ionized forms (salts) of local anesthetics are not readily absorbed through intact skin. However, both nonionized (bases) and ionized forms of local anesthetics are readily absorbed through traumatized or abraded skin into the systemic circulation.
DFOA side effects and Toxicity
Subcutaneous LD50 in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
DFOA Patient Information
No information avaliable
DFOA Organisms Affected
Humans and other mammals
