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Cyclorin Brand names, Cyclorin Analogs

Cyclorin Brand Names Mixture

  • No information avaliable

Cyclorin Chemical_Formula

C3H6N2O2

Cyclorin RX_link

No information avaliable

Cyclorin fda sheet

Cyclorin msds (material safety sheet)

Cyclorin MSDS

Cyclorin Synthesis Reference

No information avaliable

Cyclorin Molecular Weight

102.092 g/mol

Cyclorin Melting Point

147 oC

Cyclorin H2O Solubility

Soluble

Cyclorin State

Solid

Cyclorin LogP

-1.631

Cyclorin Dosage Forms

Capsules (red and gray capsules, oral, 250mg)

Cyclorin Indication

Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).

Cyclorin Pharmacology

Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria

Cyclorin Absorption

Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.

Cyclorin side effects and Toxicity

Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.

Cyclorin Patient Information

Cyclorin Organisms Affected

Enteric bacteria and other eubacteria