Cyclocapron
Cyclocapron Brand names, Cyclocapron Analogs
Cyclocapron Brand Names Mixture
- No information avaliable
Cyclocapron Chemical_Formula
C21H28N2O5
Cyclocapron RX_link
http://www.rxlist.com/cgi/generic3/trimethbenz.htm
Cyclocapron fda sheet
Cyclocapron msds (material safety sheet)
Cyclocapron Synthesis Reference
No information avaliable
Cyclocapron Molecular Weight
388.458 g/mol
Cyclocapron Melting Point
188.7 oC
Cyclocapron H2O Solubility
40 mg/L
Cyclocapron State
Solid
Cyclocapron LogP
2.784
Cyclocapron Dosage Forms
Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)
Cyclocapron Indication
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Cyclocapron Pharmacology
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Cyclocapron Absorption
The relative bioavailability of the capsule formulation compared to the solution is 100%.
Cyclocapron side effects and Toxicity
Oral LD50 in mice is 1600 mg/kg.
Cyclocapron Patient Information
No information avaliable
Cyclocapron Organisms Affected
Humans and other mammals
