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Corolin Brand names, Corolin Analogs

Corolin Brand Names Mixture

  • No information avaliable

Corolin Chemical_Formula

C25H38O5

Corolin RX_link

http://www.rxlist.com/cgi/generic/simva.htm

Corolin fda sheet

Corolin FDA

Corolin msds (material safety sheet)

Corolin Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Corolin Molecular Weight

418.566 g/mol

Corolin Melting Point

135-138oC

Corolin H2O Solubility

0.76 mg/L

Corolin State

Solid

Corolin LogP

4.937

Corolin Dosage Forms

Tablet (oral)

Corolin Indication

For the treatment of hypercholesterolemia.

Corolin Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Corolin Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Corolin side effects and Toxicity

No information avaliable

Corolin Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Corolin Organisms Affected

Humans and other mammals