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Coreg Brand names, Coreg Analogs

Coreg Brand Names Mixture

  • No information avaliable

Coreg Chemical_Formula


Coreg RX_link

Coreg fda sheet

Coreg FDA

Coreg msds (material safety sheet)

Coreg MSDS

Coreg Synthesis Reference

No information avaliable

Coreg Molecular Weight

406.474 g/mol

Coreg Melting Point

114-115 oC

Coreg H2O Solubility

Practically insoluble (0.583 mg/L)

Coreg State


Coreg LogP


Coreg Dosage Forms


Coreg Indication

For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin.

Coreg Pharmacology

Carvedilol is a nonselective beta-adrenergic blocking agent with alpha1-blocking activity and is indicated for the treatment of hypertension and mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin. Carvedilol is a racemic mixture in which nonselective b-adrenoreceptor blocking activity is present in the S(-) enantiomer and a-adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilol has no intrinsic sympathomimetic activity. The effect of carvedilol's b-adrenoreceptor blocking activity has been demonstrated in animal and human studies showing that carvedilol (1) reduces cardiac output in normal subjects; (2) reduces exercise-and/or isoproterenol-induced tachycardia and (3) reduces reflex orthostatic tachycardia.

Coreg Absorption

Carvedilol is rapidly and extensively absorbed following oral administration, with an absolute bioavailability of approximately 25% to 35% due to a significant degree of first-pass metabolism.

Coreg side effects and Toxicity

Not expected to be toxic following ingestion.

Coreg Patient Information

Patients taking COREG (Carvedilol) should be advised of the following:

  • they should not interrupt or discontinue using COREG without a physician's advice.
  • congestive heart failure patients should consult their physician if they experience signs or symptoms of worsening heart failure such as weight gain or increasing shortness of breath.
  • they may experience a drop in blood pressure when standing, resulting in dizziness and, rarely, fainting. Patients should sit or lie down when these symptoms of lowered blood pressure occur.
  • if patients experience dizziness or fatigue, they should avoid driving or hazardous tasks.
  • they should consult a physician if they experience dizziness or faintness, in case the dosage should be adjusted.
  • they should take COREG with food.
  • diabetic patients should report any changes in blood sugar levels to their physician.
  • contact lens wearers may experience decreased lacrimation.

Coreg Organisms Affected

Humans and other mammals