Contalyl

Contalyl Brand names, Contalyl Analogs

Contalyl Brand Names Mixture

No information avaliable

Contalyl Chemical_Formula

C₁₆H₁₆ClN₃O₃S

Contalyl RX_link

http://www.rxlist.com/cgi/generic2/metolazone.htm

Contalyl fda sheet

Contalyl FDA

Contalyl msds (material safety sheet)

Contalyl Synthesis Reference

No information avaliable

Contalyl Molecular Weight

365.835 g/mol

Contalyl Melting Point

256 ^oC

Contalyl H₂O Solubility

60.3 mg/L

Contalyl State

Solid

Contalyl LogP

2.784

Contalyl Dosage Forms

Tablet for oral administration (0.5mg)

Contalyl Indication

For the treatment of hypertension, alone or in combination with other antihypertensive drugs of a different class.

Contalyl Pharmacology

Metolazone is a quinazoline diuretic, with properties generally similar to the thiazide diuretics. A proximal action of metolazone has been shown in humans by increased excretion of phosphate and magnesium ions and by a markedly increased fractional excretion of sodium in patients with severely compromised glomerular filtration. This action has been demonstrated in animals by micropuncture studies.

Contalyl Absorption

Peak blood levels are obtained within 2 to 4 hours of oral administration.

Contalyl side effects and Toxicity

Symptoms of overdose include difficulty breathing, dizziness, dizziness on standing up, drowsiness, fainting, irritation of the stomach and intestines, and lethargy leading to coma.

Contalyl Patient Information